Algorithm Development & Validation

We develop and validate claims-based and EHR/EMR-based algorithms to accurately identify medical conditions and health outcomes for pharmacoepidemiology, epidemiology, comparative effectiveness research, HEOR, health outcomes research, drug safety, and pharmacovigilance. Built using clinically grounded logic and rigorous methodological standards ensuring accuracy, reproducibility, and regulatory readiness.

Algorithm Development: Transparent, Reproducible, Regulatory-Ready

Transparent glass box containing a clinical algorithm flowchart, with validation metrics showing high sensitivity, high specificity, and validated PPV

Deliverables: Detailed logic specifications, code lists, and audit-ready documentation for regulatory and HTA submissions.

Our Approach

Clinically informed outcome and phenotype definition
Transparent rule-based and hybrid algorithm design
Use of standardized medical vocabularies and data models
Validation using established metrics (PPV, sensitivity, specificity)
Documentation aligned with regulatory, HTA, and publication expectations

Deliverables

Claims- and EHR-based outcome identification algorithms
Detailed logic specifications and code lists
Validation plans and performance results
Audit-ready documentation for regulatory and HTA submissions

Discuss Your Project With Us

Ready to get started? Our team of clinicians and researchers is here to help.

Get in Touch